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AGenerally acceptableControlled studies in pregnant women show no evidence of fetal risk.

Amlodipine can pass into breast milkbut effects on the nursing baby are not knownTell your doctor if you are breast-feeding.

Numerous antihypertensive drugsfrom a variety of pharmacologic classes and with different mechanisms of actionhave been shown in randomized controlled trials to reduce cardiovascular morbidity and mortalityand it can be concluded that it is blood pressure reductionand not some other pharmacologic property of the drugsthat is largely responsible for those benefitsThe largest and most consistent cardiovascular outcome benefit has been a reduction in the risk of strokebut reductions in myocardial infarction and cardiovascular mortality also have been seen regularly.

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